P294 BIOPROSTHETIC AORTIC VALVE REPLACEMENT IN PATIENTS AT INCREASED RISK OF EARLY STRUCTURAL VALVE DEGENERATION

Abstract Background Biological prostheses are increasingly been used in young patients to avoid anticoagulation. The Edwards Inspiris aortic bioprosthesis is extremely promising this population, since it has shown reduced calcification of the prosthetic leaflets preclinical and early clinical studies. Little data available, however, younger than 65. This study investigates hemodynamic performance outcome aged 56 ± 10.7 years. Methods Results Between may 2018 December 2022, 342 years underwent AVR with at our institution. 37 them (10.8%) were 40, 98 (28.6%) had a BMI >30 kgm2. A minimally invasive approach was all isolated patients. Associated procedures performed 157 (45.9%) There redo (16.4%). 7 died (2%). Major complications included bleeding (32), respiratory failure (20) BAV requiring PMK (4). mean follow up 23 15.2 months (range 2–55). Late valve–related events endocarditis (5) reoperation. no thromboembolic events, valve thrombosis or SVD cases. At up, except four reported significant improvement their symptomatic status (98.8% NYHA II) quality life. Conclusion Our demonstrates excellent haemodynamics results cohort very Further studies longer follow–up needed.